We investigate how mosquito innate immunity and host metabolic conditions regulate vector competence for arboviruses and malaria parasites — paving the way for novel transmission-blocking strategies.
Blood from diet-induced obese and diabetic mice remodels Aedes aegypti gut metabolism and reduces Zika virus infections, establishing a novel immunometabolic axis in arbovirus transmission.
Double peroxidase and histone acetyltransferase AgTip60 maintain immune memory in primed mosquitoes — the first mechanistic description of trained immunity in vectors.
Comprehensive analyses tracing the major components of innate immunity across animal evolution, connecting mammalian trained immunity to invertebrate systems.
Core line. Does an insect remember an infection? Epigenetic regulation of the primed immune state in mosquitoes.
Core line. What the blood meal does to the vector — host metabolic state as a variable in transmission.
Core line. How old are the parts of immunity? Tracing innate immunity across animals, from cnidarians to mammals.
Derived. Applying species distribution and statistical modelling to vector-borne transmission.
Derived. The insect gut seen up close — the frontier where digestion and infection are decided.
Derived. Where immunology meets agriculture, in the soybean pest Anticarsia gemmatalis.
Additional line. An ancient molecule at the meeting point of cell physiology, metabolism, virulence and immunity.
Associate Professor at IBCCF/UFRJ. Ph.D. in Biological Sciences — Biophysics (UFRJ, 2012). Intramural Fellow at NIH/NIAID, postdoctoral researcher at Johns Hopkins, and Marie Skłodowska-Curie Fellow at CNRS (Paris). Coordinates the Vector Insects Platform, the Graduate Programme in Parasitology and Cell Biology, and the PPGP-TBB; Vice-Director of the Advanced Microscopy Unit (UMA) at CENABIO.
Fabio M. Gomes was awarded a CNPq Research Productivity Fellowship, alongside the ongoing JCNE grant from FAPERJ.
How host overweight and insulin resistance modulate the vector capacity of Aedes aegypti.
Invited lecture at the 1st Workshop on Fundamentals and Applications of Fluorescence Microscopy, Campinas.
Three fronts — microscopy and imaging, biochemistry and molecular biology, and omics.
We are recruiting undergraduate, master's and doctoral students across three fronts — imaging, bench biochemistry and data. Curiosity and care with protocol count for more than arriving knowing everything.